| Identification | Back Directory | [Name]
(R)-5-(3-chlorophenyl)-3-(1-((4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)oxy)ethyl)isoxazole | [CAS]
934282-55-0 | [Synonyms]
AZD2066)
AZD 2066
(AZD-2066
4-[5-[(1R)-1-[5-(3-Chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine
Pyridine, 4-[5-[(1R)-1-[5-(3-chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]-
(R)-5-(3-chlorophenyl)-3-(1-((4-Methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)oxy)ethyl)isoxazole | [Molecular Formula]
C19H16ClN5O2 | [MDL Number]
MFCD22420281 | [MOL File]
934282-55-0.mol | [Molecular Weight]
381.82 |
| Chemical Properties | Back Directory | [Melting point ]
140-142°C | [Boiling point ]
626.3±65.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.91±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
AZD 2066 is a mGluR5 anatagonist that is used for treating and preventing pain, neurological, psychiatric and other diseases. | [Biological Activity]
AZD2066 is an orally bioavailablebrain penetrantselective and potent negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5). AZD2066 exhibited satisfactory efficacy in patients suffering from neuropathic pain with mechanical hypersensitivity. | [storage]
Store at -20°C |
|
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BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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R&D Systems, Inc
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18003437475 18003437475 |
| Website: |
www.rndsystems.com |
| Company Name: |
Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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