ChemicalBook--->CAS DataBase List--->934739-29-4

934739-29-4

934739-29-4 Structure

934739-29-4 Structure
IdentificationBack Directory
[Name]

Karavilagenin D
[CAS]

934739-29-4
[Synonyms]

Karavilagenin D
[Molecular Formula]

C30H46O4
[MDL Number]

MFCD20274856
[MOL File]

934739-29-4.mol
[Molecular Weight]

470.684
Chemical PropertiesBack Directory
[Boiling point ]

595.8±50.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

14.54±0.29(Predicted)
Hazard InformationBack Directory
[Description]

Karavilagenin D exhibits inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator, and with TPA as a promoter. Karavilagenin D exhibits inhibition effect against human cancer cell lines.
[Uses]

Karavilagenin D, a cucurbitane-type triterpene isolated from Japanese bitter melon leaves, is a potential tumor-promoting inhibitor[1].
[References]

[1] Jie Zhang, et al. Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities. Chem Biodivers. 2012 Feb;9(2):428-40. DOI:10.1002/cbdv.201100142
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