| Identification | Back Directory | [Name]
Tosyl azide | [CAS]
941-55-9 | [Synonyms]
Tosyl azide
Tosyl azide solution
p-Toluenesulfonyl azide
P-toluenesulfonyl azide or
4-methyl-benzenesulfonylazid
4-Methylbenzenesulfonyl azide
p-Methylbenzenesulfonyl azide
p-Toluenesulfonazide solution
Benzenesulfonylazide,4-methyl-
p-Toluenesulfonyl azide solution
4-Methylbenzenesulfonic acid azide
p-Methylbenzenesulfonic acid azide
Tosyl azide (75% in ethyl acetate)
p-Toluenesulfonyl azide,Tosyl azide
p-Toluenesulfonyl azide solution, 98%+
4-Methylbenzenesulfonyl azide solution
p-Toluenesulfonyl azide, 99%, 25% in Ethyl acetate
P-TOLUENESULFONYL AZIDE OR 4-METHYLBENZENESULFONYL AZIDE
p-Toluenesulfonyl azide solution11-15 % (w/w) in Toluene,
≥ 99% (HPLC) | [EINECS(EC#)]
213-381-5 | [Molecular Formula]
C7H7N3O2S | [MDL Number]
MFCD00180767 | [MOL File]
941-55-9.mol | [Molecular Weight]
197.21 |
| Questions And Answer | Back Directory | [Synthesis]
At room temperature, 13.8 g of p-toluenesulfonyl chloride (73 mmol), 50 mL of water, and 5.7 g of sodium azide (87 mmol) were added sequentially to a 500 mL flask. The mixture was stirred for 2 hours, and the reaction was monitored by TLC until complete. The mixture was then extracted three times with 50 mL of dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate, and concentrated to obtain 12.7 g of Tosyl azide product, with a yield of 88%. | [Description]
Tosyl azide is a reagent used in organic synthesis. It is prepared by the reaction of tosyl chloride with sodium azide in aqueous acetone.
| [Applications]
Tosyl azide is utilized for the introduction of diazo and azide functional groups. Moreover, it is used as a nitrene and a substrate for [3+2] cycloaddition reactions.
| [Safety]
Tosyl azide is a very volatile chemical that should be carefully stored and handled.
|
| Chemical Properties | Back Directory | [Melting point ]
22 °C | [density ]
~0.90 g/mL at 20 °C | [refractive index ]
n20/D 1.548 | [Fp ]
4℃ | [storage temp. ]
2-8°C | [form ]
liquid | [InChI]
InChI=1S/C7H7N3O2S/c1-6-2-4-7(5-3-6)13(11,12)10-9-8/h2-5H,1H3 | [InChIKey]
NDLIRBZKZSDGSO-UHFFFAOYSA-N | [SMILES]
C1(C=CC(C)=CC=1)S(=O)(=O)N=[N+]=[N-] | [EPA Substance Registry System]
Benzenesulfonyl azide, 4-methyl-(941-55-9) |
|
| Company Name: |
skychemical Co.Ltd Gold
|
| Telephone: |
021-20960837,QQ1332204249 |
| Website: |
http://www.skychemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
skychemical Co.Ltd
|
| Telephone: |
021-20958197 20965099 |
| Website: |
www.skychemical.com |
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