| Identification | Back Directory | [Name]
sodium 2-[4-(1,3-dihydro-1-oxo-2H-isoindol-2-ylthio)phenyl]butyrate | [CAS]
94135-04-3 | [Synonyms]
Indobufen sodium
sodium 2-[4-(1,3-dihydro-1-oxo-2H-isoindol-2-ylthio)phenyl]butyrate
4-[[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]thio]-α-ethylbenzeneacetic acid sodium salt | [EINECS(EC#)]
302-872-0 | [Molecular Formula]
C18H16NNaO3S | [MOL File]
94135-04-3.mol | [Molecular Weight]
349.379 |
| Hazard Information | Back Directory | [Uses]
Indobufen sodium is a platelet aggregation inhibitor. Indobufen sodium is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen sodium suppresses thromboxane A2 (TxA2) synthesis. Indobufen sodium down-regulates tissue factor (TF) in monocytes[1]. | [References]
[1] Eligini S, et al. Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. Cardiovasc Res. 2006 Jan;69(1):218-26. DOI:10.1016/j.cardiores.2005.07.013 |
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