| Identification | Back Directory | [Name]
3-Isoxazolecarboxamide, N-(3-chloro-4-fluorophenyl)-5-(2-methylpropyl)- | [CAS]
945189-68-4 | [Synonyms]
SJ000063181
3-Isoxazolecarboxamide, N-(3-chloro-4-fluorophenyl)-5-(2-methylpropyl)- | [Molecular Formula]
C14H14ClFN2O2 | [MOL File]
945189-68-4.mol | [Molecular Weight]
296.72 |
| Chemical Properties | Back Directory | [Boiling point ]
350.8±42.0 °C(Predicted) | [density ]
1.308±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml | [form ]
Solid | [pka]
9.60±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SJ000063181 is a potent BMP signaling activator with an EC50 ≤1 μM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos[1]. | [References]
[1] Jamie R Genthe, et al. Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. ACS Chem Biol.2019 Jul 19;14(7):1673. DOI:10.1021/acschembio.9b00488 |
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