| Identification | Back Directory | [Name]
CYCLOPHILIN A | [CAS]
95076-93-0 | [Synonyms]
EC 5.2.1.8
CYCLOPHILIN
CYCLOPHILIN A
CYCLOPHILIN HUMAN
CYCLOPHILIN A (HUMAN)
CYCLOPHILIN FROM CALF THYMUS
cyclophilin a from calf thymus
PEPTIDYLPROLINE CIS-TRANS-ISOMERASE
Cyclophilin A from Human, Recombinant
CYCLOPHILIN HUMAN, RECOMBINANTEXPRESSED IN E. COLI | [MDL Number]
MFCD00130885 |
| Hazard Information | Back Directory | [Uses]
Cyclophilin A human has been used in the study to interpret the mechanisms by which extracellular CyPA initiates endothelial activation. | [General Description]
Cyclophilins are a family of extremely conserved proteins, known as immunophilins. Cyclophilin A (CyPA) is present in all tissues in prokaryotes and eukaryotes. It is present in all organs of human. Cyclophilin A (CyPA), a 20 kDa chaperone protein, that is liberated from vascular smooth muscle cells (VSMCs). | [Biochem/physiol Actions]
Cyclophilin A (CyPA) participates in intracellular signalling and protein trafficking. It helps to control other proteins activity. CyPA plays a physiological and pathological role in cardiovascular diseases. Hence it acts as an important biomarker and mediator in several cardiovascular diseases, like vascular stenosis, atherosclerosis and abdominal aortic aneurysms.?CyPA can induce the proliferation and inflammatory cell migration of vascular smooth muscle cells (VSMC) in vitro and in vivo. |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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