| Identification | Back Directory | [Name]
bis((9-acridinyl)seryl-alanyl-cysteinyl-valine)dilactone disulfide | [CAS]
95676-71-4 | [Synonyms]
Basacv
bis((9-acridinyl)seryl-alanyl-cysteinyl-valine)dilactone disulfide
7,20-bis(acridin-9-ylamino)-4,17-dimethyl-11,24-di(propan-2-yl)-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexazabicyclo[12.12.4]triacontane-3,6,10,13,16,19,23,26-octone | [Molecular Formula]
C54H60N10O10S2 | [MOL File]
95676-71-4.mol | [Molecular Weight]
1073.25 |
| Hazard Information | Back Directory | [Description]
Basacv is a bisacridinyl peptidic analog of triostin A. | [Uses]
Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator[1]. | [References]
[1] Helbecque N, et al. Design of a new DNA-polyintercalating drug, a bisacridinyl peptidic analogue of Triostin A. Biochem J. 1985 Feb 1;225(3):829-32. DOI:10.1042/bj2250829 |
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