| Identification | Back Directory | [Name]
NVP-QAV-572 | [CAS]
957209-68-6 | [Synonyms]
CS-1461
NVP-QAV-572
1-[2-[2-(2-fluoroethyl)tetrazol-5-yl]ethyl]-3-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]urea
N-[2-[2-(2-Fluoroethyl)-2H-tetrazol-5-yl]ethyl]-N'-[5-[3-fluoro-4-(methylsulfonyl)phenyl]-4-methyl-2-thiazolyl]urea | [Molecular Formula]
C17H19F2N7O3S2 | [MDL Number]
MFCD25976833 | [MOL File]
957209-68-6.mol | [Molecular Weight]
471.5 |
| Chemical Properties | Back Directory | [density ]
1.59±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (265.11 mM; Need ultrasonic) | [form ]
Powder | [pka]
6.27±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM. | [IC 50]
PI3K: 10 nM (IC50) | [References]
[1] Emma Budd, et al. 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors. US 7998990 B2. |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
|