| Identification | Back Directory | [Name]
FPH2 | [CAS]
957485-64-2 | [Synonyms]
FPH2
CS-2516
BRD-9424
FPH2(BRD-9424)
4-[3-(5-Chloro-2-methoxyphenyl)thioureido]-1-ethyl-1H-pyrazole-3-carboxamide
4-(3-(5-Chloro-2-methoxyphenyl)thioxureido)-1-ethyl-1H-pyrazole-3-carboxamide
4-[(5-chloro-2-methoxyphenyl)carbamothioylamino]-1-ethylpyrazole-3-carboxamide
4-[[[(5-chloro-2-methoxyphenyl)amino]thioxomethyl]amino]-1-ethyl-1H-pyrazole-3-carboxamide
1H-Pyrazole-3-carboxamide, 4-[[[(5-chloro-2-methoxyphenyl)amino]thioxomethyl]amino]-1-ethyl- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C14H16ClN5O2S | [MDL Number]
MFCD04137604 | [MOL File]
957485-64-2.mol | [Molecular Weight]
353.83 |
| Chemical Properties | Back Directory | [Boiling point ]
537.5±60.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [pka]
11.31±0.70(Predicted) | [color ]
white to beige | [InChI]
InChI=1S/C14H16ClN5O2S/c1-3-20-7-10(12(19-20)13(16)21)18-14(23)17-9-6-8(15)4-5-11(9)22-2/h4-7H,3H2,1-2H3,(H2,16,21)(H2,17,18,23) | [InChIKey]
PCHRYHSDDPPZBV-UHFFFAOYSA-N | [SMILES]
N1(CC)C=C(NC(NC2=CC(Cl)=CC=C2OC)=S)C(C(N)=O)=N1 |
| Hazard Information | Back Directory | [Description]
BRD-9424, also known as functional proliferation hit 2 (FPH2), is a small molecule that induces proliferation of primary human hepatocytes in vitro. | [Uses]
FPH2 induces of functional proliferation of primary human hepatocytes and may lead to the development of new therapeutics for liver diseases. | [Definition]
ChEBI: 4-[[(5-chloro-2-methoxyanilino)-sulfanylidenemethyl]amino]-1-ethyl-3-pyrazolecarboxamide is a member of thioureas. | [References]
[1]. shan j, schwartz re, ross nt, et al. identification of small molecules for human hepatocyte expansion and ips differentiation. nat chem biol, 2013, 9(8): 514-520. |
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| Company Name: |
Lynnchem
|
| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
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