| Identification | Back Directory | [Name]
BNDPDYQQAJUJPY-SFHVURJKSA-N | [CAS]
957889-73-5 | [Synonyms]
(S)-BI-1001
BNDPDYQQAJUJPY-SFHVURJKSA-N | [Molecular Formula]
C19H15BrClNO3 | [MDL Number]
MFCD28386158 | [MOL File]
957889-73-5.mol | [Molecular Weight]
420.684 |
| Hazard Information | Back Directory | [Description]
BI-1001 is an allosteric HIV-1 integrase (IN) inhibitor (ALLINI). | [Uses]
(S)-BI-1001 (Compound 11) is an active S-enantiomer of BI-1001. (S)-BI-1001 exhibits antiviral potency against HIV-1 integrase with an IC50 of 28 nM, an EC50 of 450 nM and a Kd of 4.7 μM[1]. | [References]
[1] Fader LD, et al. Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1. ACS Med Chem Lett. 2014 Jan 22;5(4):422-7. DOI:10.1021/ml500002n |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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