ChemicalBook--->CAS DataBase List--->96323-41-0

96323-41-0

96323-41-0 Structure

96323-41-0 Structure
IdentificationBack Directory
[Name]

D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE
[CAS]

96323-41-0
[Synonyms]

S2288
S-2288(2HCl)
D-Ile-Pro-Arg p-nitroanilide
D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE
(2S)-1-[(2R,3R)-2-amino-3-methylpentanoyl]-N-[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
[Molecular Formula]

C23H37ClN8O5
[MDL Number]

MFCD00792772
[MOL File]

96323-41-0.mol
[Molecular Weight]

541.05
Chemical PropertiesBack Directory
[solubility ]

water: 1 mg/mL, clear, colorless to faintly yellow
[form ]

powder
[color ]

White to off-white
[Water Solubility ]

water: 1mg/mL, clear, colorless to faintly yellow
[InChIKey]

YSYQQKNJMACZCI-ASLVLMPBNA-N
[SMILES]

C([C@@H]1CCCN1C(=O)[C@H](N)[C@H](C)CC)(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1.Cl |&1:1,8,10,16,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332-H315-H319-H335-H361-H373
[Precautionary statements ]

P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-33-36/37/38-63
[Safety Statements ]

28-36/37-45
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA)[1].
[References]

[1] Chmielewska J, et al. Kinetics of the inhibition of plasminogen activators by the plasminogen-activator inhibitor. Evidence for 'second-site' interactions. Biochem J. 1988 Apr 15;251(2):327-32. DOI:10.1042/bj2510327
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