| Identification | More | [Name]
L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE | [CAS]
40127-11-5 | [Synonyms]
H-ARG-PNA 2HCL
H-arg-pna.2hci
L-Arg-pNA·2HCl
H-ARG-PNA 2HBR
H-Arg-PNA..HCl
H-L-ARG-PNA 2HBR
H-L-ARG-PNA 2HCL
ARGININE-PNA 2 HCL
H-Arg-pNA.Dihydrochloride
L-Arginine p-nitroanilide
L-Arginine p-nitroanilide DiHCl
ARGININE P-NITROANILIDE DIHYDROBROMIDE
ARGININE P-NITROANILIDE DIHYDROCHLORIDE
L-ARGININE 4-NITROANILIDE DIHYDROBROMIDE
L-ARGININE 4-NITROANILIDE DIHYDROCHLORIDE
L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE
L- arginine onnitroanilidetwohydrochloride
L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE USP/EP/BP
L-Arginine 4-nitroanilide dihydrochloride≥ 98% (HPLC)
(S)-2-amino-5-guanidino-N-(4-nitrophenyl)pentanamide dihydrobromide
(S)-2-Amino-5-guanidino-N-(4-nitrophenyl)-pentanamide dihydrochloride
(2S)-2-amino-5-(diaminomethylideneamino)-N-(4-nitrophenyl)pentanamide
(2S)-2-amino-5-carbamimidamido-N-(4-nitrophenyl)pentanamide dihydrochloride
(2S)-2-Amino-5-[(aminoiminomethyl)amino]-N-(4-nitrophenyl)pentanamide dihydrochloride | [Molecular Formula]
C12H20Cl2N6O3 | [MDL Number]
MFCD00058249 | [Molecular Weight]
367.23 | [MOL File]
40127-11-5.mol |
| Questions And Answer | Back Directory | [Preparation]
L-arginine, p-nitroaniline, and potassium carbonate were mixed, acetonitrile was added, and the mixture was heated to 80 °C for 2 h. Thin-layer chromatography analysis showed that the reaction was complete. The mixture was filtered, evaporated to dryness under reduced pressure, and the concentrate was purified by column chromatography to prepare a yellow solid H-arginine-PNA. The solid was then acidified with hydrochloric acid to prepare the target compound L-ARGININE P-NITROANILIDE DIHYDROCHLORIDE. |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Solid | [color ]
Off-white to light yellow | [Optical Rotation]
Consistent with structure | [InChI]
1S/C12H18N6O3.ClH/c13-10(2-1-7-16-12(14)15)11(19)17-8-3-5-9(6-4-8)18(20)21;/h3-6,10H,1-2,7,13H2,(H,17,19)(H4,14,15,16);1H/t10-;/m0./s1 | [InChIKey]
KBODDOUNTSALJF-PPHPATTJSA-N | [SMILES]
Cl.N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O | [CAS DataBase Reference]
40127-11-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellowish powder | [Uses]
Specific substrate for cathepsin H. | [Biological Activity]
p-Nitroanilides derivatives of amino acids are mostly used as chromogenic substrates for measuring the activity of proteolytic enzymes. |
|
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Energy Chemical
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Sigma-Aldrich
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Shanghai GL Peptide Ltd.
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