| Identification | Back Directory | [Name]
Cyclethrin | [CAS]
97-11-0 | [Synonyms]
ENT-22952 PYPYRETHRIN) American cyanamid-43064 Cyclethrin ISO 9001:2015 REACH Cyclopentenylrethonyl chrysanthemate 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid 3-(2-cyclopentenyl)-2-methyl-4-oxo-2-cyclopentenyl [3-(1-cyclopent-2-enyl)-2-methyl-4-oxo-1-cyclopent-2-enyl] 2,2-dimethy l-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 3-(2-cyclopenten-1-yl)-2-methyl-4-oxo-2-cyclopenten-1-yl ester | [Molecular Formula]
C21H28O3 | [MDL Number]
MFCD01735822 | [MOL File]
97-11-0.mol | [Molecular Weight]
328.449 |
| Hazard Information | Back Directory | [Uses]
Insecticide for flies, roaches, and grain pests. | [Description]
Cyclethrin is a pyrethroid insecticide. Little data has been published on its environmental fate, ecotoxicology or its impact on human health. | [Production Methods]
The production of cyclethrin involves a multi-step organic synthesis centred around esterification and cyclopropane ring formation. The process begins with the preparation of a cyclopentenone derivative, which is then functionalised to introduce a cyclopent-2-en-1-yl group. Separately, a cyclopropane carboxylic acid derivative, typically bearing a 2-methylprop-1-enyl side chain, is synthesised, often using diazo compounds or Simmons–Smith-type reactions to construct the strained ring. These two key intermediates are then coupled via esterification, forming the final molecule. | [Mechanism of action]
Contact and stomach action. Sodium channel modulator. | [Pesticide Type]
Insecticide; Veterinary substance |
| Safety Data | Back Directory | [RIDADR ]
3082 | [HazardClass ]
9 | [PackingGroup ]
III | [Safety Profile]
Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes. See also other pyrethrin entries. | [Toxicity]
LD50 orally in rats: 1.4-2.8 g/kg (Carpenter) |
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