ChemicalBook--->CAS DataBase List--->97845-62-0

97845-62-0

97845-62-0 Structure

97845-62-0 Structure
IdentificationBack Directory
[Name]

1,9-Dihydro-2-amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-on e monosodium salt
[CAS]

97845-62-0
[Synonyms]

Denavir
Unii-p06226385l
PENCICLOVIR SODIUM
sodium 4-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-2-(hy droxymethyl)butan-1-olate
2-Amino-1,9-dihydro-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-one monosodium salt
1,9-Dihydro-2-amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-on e monosodium salt
[Molecular Formula]

C10H14N5O3*Na
[MOL File]

97845-62-0.mol
[Molecular Weight]

277.26
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

>41.7mg/mL in DMSO
[form ]

Powder
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315-H335
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Uses]

Antiviral(treatment of herpes virus infections).
[Brand name]

Denavir (Novartis).
[in vivo]

Penciclovir sodium (100 mg/kg; s.c.; daily for 5 days) preventes mortality in mouse[2].

Animal Model:Three-week-old female Balb/c mice[2]
Dosage:100 mg/kg
Administration:S.c.; daily for 5 days
Result:Reduced virus titres in the respiratory organs of both w/t- and PR3-infected mice.
[IC 50]

HSV-1: 0.5 μg/mL (EC50); HSV-2: 0.8 μg/mL (EC50)
[storage]

Store at -20°C
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