| Identification | Back Directory | [Name]
3,4'-Dihydroxy-3',5,7-trimethoxyflavan | [CAS]
97914-19-7 | [Synonyms]
3,4'-DIHYDROXY-3',5,7-TRIMETHOXY
3,4'-Dihydroxy-3',5,7-trimethoxyflavan
2-(4-Hydroxy-3-Methoxyphenyl)-5,7-diMethoxychroMan-3-ol
(2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-5,7-dimethoxychroman-3-ol | [Molecular Formula]
C18H20O6 | [MDL Number]
MFCD19441000 | [MOL File]
97914-19-7.mol | [Molecular Weight]
332 |
| Chemical Properties | Back Directory | [Boiling point ]
541.1±50.0 °C(Predicted) | [density ]
1.283±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.81±0.35(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer [1]. | [References]
[1] Lee JS, et al. Inhibition of phospholipase Cgamma1 and cancer cell proliferation by lignans and flavans from Machilus thunbergii. Arch Pharm Res. 2004 Oct;27(10):1043-7 DOI:10.1007/BF02975429 |
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