108351-91-3
108351-91-3 结构式
物理化学性质
熔点129-132 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
沸点383.6±30.0 °C(Predicted)
密度1.182±0.06 g/cm3(Predicted)
酸度系数(pKa)7.04±0.40(Predicted)
应用领域
用途一
PD 120697 is a dopamine antagonist. It is a novel class of compounds with central dopamine agonist properties. It has been identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests that include [3H]-haloperidol and [3H]-N-propylnorapomorphine binding, inhibition of striatal DA synthesis, inhibition of DA neuronal firing, inhibition of spontaneous locomotor activity, and reversal of reserpine-induced depression in rats.