120020-26-0
120020-26-0 结构式
基本信息
中文别名
化合物 T10378 英文别名
Artelinateartelinic acid
beta-Artelinic acid
(3R,5aα,8aα,12aR)-Decahydro-10β-(4-carboxybenzyloxy)-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin
(3R,5aα,8aα,12aR)-Decahydro-3,6α,9β-trimethyl-10α-(4-carboxybenzyloxy)-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin
Benzoic acid, 4-[[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]methyl]-
120020-26-0价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-135578 | Artelinic acid | 120020-26-0 | 1 mg | 1150元 |
| 2025/05/22 | HY-135578 | Artelinic acid | 120020-26-0 | 10 mM * 1 mLin DMSO | 2762元 |
| 2025/05/22 | HY-135578 | 120020-26-0 Artelinic acid | 120020-26-0 | 5mg | 3000元 |
常见问题列表
生物活性
Artelinic acid，青蒿素衍生物，可用于恶性疟原虫多药耐药的抗疟研究。Artelinic acid 可以通过各种途径给药，包括静脉、肌肉和口服途径。体内研究
Artelinic acid (10 mg/kg; i.v.) has an elimination time t
1/2
of 0.37 hours, a CL of 14.99 mL/min/kg, a V
ss
of 9.52 L and a AUC
0-12h
of 11219 ng h/mL for dogs.
Artelinic acid (10 mg/kg; intramuscular) has an elimination time t
1/2
of 6.14 hours, a CL of 14.58 mL/min/kg, a V
ss
of 36.1 L and a AUC
0-12h
of 96372 ng h/mL for dogs.
Artelinic acid (10 mg/kg; oral) has an elimination time t
1/2
of 2.21 hours, a CL of 14.6 mL/min/kg, a V
ss
of 16.2 L and a AUC
0-12h
of 8839 ng h/mL for dogs.
| Animal Model: | Adult male beagle dogs 3-5 years old |
| Dosage: | 10 mg/kg |
| Administration: | i.v. (Pharmacokinetic Analysis) |
| Result: | Had an elimination time t 1/2 of 0.37 hours, a CL of 14.99 mL/min/kg, a V ss of 9.52 L and a AUC 0-12h of 11219 ng h/mL for dogs. |