SFOM-0046 is an anticancer agent. It arrests the cell cycle in S-phase and causes DNA replication stress, leading to the phosphorylation of H2AX into gamma-H2AX.
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概述
SFOM-0046 可以使细胞周期停滞在 S 期，并引起 DNA 复制应激，导致 H2AX 磷酸化为 γ-H2AX。SFOM-0046 会诱导 DNA 损伤。SFOM-0046 是一种有效的抗癌剂。
