138794-73-7
中文名称
138794-73-7
英文名称
CGP 48664A
CAS
138794-73-7
分子式
C11H15ClN6
分子量
266.73
MOL 文件
138794-73-7.mol
更新日期
2025/08/29 16:44:49
138794-73-7 结构式
基本信息
中文别名
化合物SARDOMOZIDE2-(4-甲脒基-2,3-二氢-1H-茚-1-亚基)肼-1-甲脒基二盐酸盐
英文别名
CGP 48664ASardomozide HCl
Sardomozide dihydrochloride
物理化学性质
储存条件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度DMSO:25.0(Max Conc. mg/mL);82.46(Max Conc. mM)
形态A solid
颜色White to off-white
138794-73-7价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-13746B | Sardomozide dihydrochloride | 138794-73-7 | 1 mg | 670元 |
| 2025/05/22 | HY-13746B | 138794-73-7 Sardomozide dihydrochloride | 138794-73-7 | 5mg | 1500元 |
| 2025/05/22 | HY-13746B | 138794-73-7 Sardomozide dihydrochloride | 138794-73-7 | 10mM * 1mLin DMSO | 1650元 |
常见问题列表
生物活性
Sardomozide dihydrochloride 是一种 S-腺苷甲硫氨酸脱羧酶 (SAMDC) 抑制剂，其 IC50 值为 5 nM。靶点
IC50: 5 nM (SAMDC)
体外研究
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.