15442-64-5
15442-64-5 结构式
基本信息
原卟啉锌
三水合原卟啉锌
原卟啉锌(II)
三水合原卟啉锌,96%
锌原卟啉(ZNPPIX)
原卟啉 IX 锌(II) 络合物
3,3'-(3,8,13,17-四甲基-7,12-二乙烯基卟啉-2,18-二基)二丙酸锌
PROTOPORPHYRINATO ZINC
Zinc protoporphyrin trihydrate
Zinc protoporphyrin trihydrate, 95+%
PROTOPORPHYRINATO ZINC ISO 9001：2015 REACH
Zinc Protoporphyrin IX DISCONTINUED, offer Z439970
Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem
Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
dihydrogen [3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]zincate(4-)
物理化学性质
≥12000 at 548-554nm in pyridine
≥135000 at 423-429nm in pyridine
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/09/19 | 032068 | 三水合原卟啉锌, 96%
Zinc protoporphyrin, 96% | 15442-64-5 | 10mg | 731元 |
| 2025/05/22 | 032068 | 三水合原卟啉锌, 96%
Zinc protoporphyrin, 96% | 15442-64-5 | 50mg | 2068元 |
| 2025/05/22 | 032068 | 原卟啉锌 Zinc protoporphyrin | 15442-64-5 | 0.25g | 8085元 |
常见问题列表
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Human Endogenous Metabolite
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Zinc Protoporphyrin (Zn(II)-protoporphyrin IX; 5 μM; 72 hours) causes the fraction of late apoptotic and necrotic cells increasing from 10.9% in controls to 30.4% after 72 h.
Zinc Protoporphyrin (1.25-40 μM; 48 or 72 hours) exerts cystostatic/cytotoxic effects against tumor cells.
Zinc Protoporphyrin (2.5, 5 μM; 48 or 72 hours) results in dose- and time-dependent reduction of cells in G1 phase of the cell cycle.
Zinc Protoporphyrin (1.25-40 μM; 48 hours) leads to accumulation of cleaved (active) caspase-3.
Apoptosis Analysis
| Cell Line: | C-26 cells |
| Concentration: | 5 μM |
| Incubation Time: | 72 hours |
| Result: | The fraction of late apoptotic and necrotic cells increased from 10.9% in controls to 30.4% after 72 h. |
Cell Cytotoxicity Assay
| Cell Line: | C-26 and MDA-MB231 cells |
| Concentration: | 1.25, 2.5, 5, 10, 20, 40 μM |
| Incubation Time: | 48 or 72 hours |
| Result: | Exerted cystostatic/cytotoxic effects against tumor cells. |
Cell Cycle Analysis
| Cell Line: | C-26 cells |
| Concentration: | 2.5, 5 μM |
| Incubation Time: | 48 or 72 hours |
| Result: | Resulted in dose- and time-dependent reduction of cells in G1 phase of the cell cycle. |
Western Blot Analysis
| Cell Line: | C-26 cells |
| Concentration: | 1.25, 2.5, 5, 10, 20, 40 μM |
| Incubation Time: | 48 hours |
| Result: | Leaded to accumulation of cleaved (active) caspase-3. |
Zinc Protoporphyrin (12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o.; from day 7 to 19) exerts dose-dependent antitumor effects manifested by the retardation of tumor growth.
| Animal Model: | BALB/c mice inoculated with C-26 cells |
| Dosage: | 12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o. |
| Administration: | IP or PO; from day 7 to 19 |
| Result: | Exerted dose-dependent antitumor effects manifested by the retardation of tumor growth. |