2221950-65-6
中文名称
2MG
英文名称
1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]-
CAS
2221950-65-6
分子式
C23H36ClN7
分子量
446.03
MOL 文件
2221950-65-6.mol
更新日期
2024/07/24 18:26:20
2221950-65-6 结构式
基本信息
英文别名
OAT-20681H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]-
应用领域
用途一
OAT-2068 is a potent, selective, and orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1). OAT-2068 displays a remarkable 143-fold mCHIT1 vs. mAMCase selectivity. OAT-2068 was found to have an excellent pharmacokinetic profile. OAT-2068 represents a highly potent and the most selective inhibitor of mCHIT1 described to date.