2244161-71-3
中文名称
Dolutegravir Impurity 7
英文名称
Dolutegravir Impurity 7
CAS
2244161-71-3
分子式
C20H21N3O5
分子量
383.4
MOL 文件
2244161-71-3.mol
2244161-71-3 结构式
基本信息
中文别名
杜鲁特韦杂质4度鲁特韦杂质7
度鲁特韦 杂质11
英文别名
Dolutegravir Impurity 72,4-Di-Desfluoro Dolutegravir Sodium salt
所属类别
分析化学：药典标准品和杂质标准品应用领域
用途一
Desdifluoro Dolutegravir is impurity B of Dolutegravir(D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.