27750-13-6
中文名称
藤黄内酯
英文名称
HYDROXYCITRIC ACID LACTONE, (-)-(P)
CAS
27750-13-6
分子式
C6H6O7
分子量
190.11
MOL 文件
27750-13-6.mol
27750-13-6 结构式
基本信息
中文别名
藤黄内酯(-)-羟基柠檬酸内酯
英文别名
Garcinia lactone(-)-Hydroxycitric acid lactone
HYDROXYCITRIC ACID LACTONE, (-)-(P)
3-C-Carboxy-2-deoxy-D-erythropentaric acid 1,4-lactone
D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone
(2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid
所属类别
分析化学：离子色谱试剂物理化学性质
沸点673.6±55.0 °C(Predicted)
密度1.976
储存条件2-8°C
溶解度DMSO : 250 mg/mL (1315.03 mM; Need ultrasonic)
酸度系数(pKa)2.40±0.40(Predicted)
形态neat
颜色White to off-white
常见问题列表
生物活性
(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种减肥药，也是一种很受欢迎的减肥食品补充剂。(-)-Hydroxycitric acid lactone 是一种有效的 ATP-柠檬酸裂解酶 抑制剂。(-)-Hydroxycitric acid lactone 催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。体内研究
(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken.
| Animal Model: | 1-day-old male broiler chickens |
| Dosage: | 1000, 2000, 3000 mg/kg |
| Administration: | Fed for a period of 4 weeks |
| Result: | Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower. |