30426-66-5

报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2023/03/20 | HY-N6894 | Isocoptisine acetate Pseudocoptisine acetate | 30426-66-5 | 1mg | 7240元 |
2023/03/20 | HY-N6894 | Isocoptisine acetate Pseudocoptisine acetate | 30426-66-5 | 5mg | 21710元 |
常见问题列表
Pseudocoptisine (0, 60, 90 μM; 1 hour) dose-dependently inhibited LPS-induced NO production in RAW264.7 cells.
Pseudocoptisine (30-90 μM; 1 hour; RAW264.7 cells) significantly reduces the LPS-induced TNF-α and IL-6 production and their mRNA expressions.
Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells.
The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) are examined. Pseudocoptisine (2.0 mg/kg, p.o.) significantly reverses cognitive impairments in mice by passive avoidance test.