55-97-0
55-97-0 结构式
基本信息
六甲溴铵
溴化六甲双铵
溴化六烃季铵
溴化六烃季铵C6
六次甲基双-1,6-溴化三甲铵
六亚甲基-1,6-双(三甲基溴化铵)
六亚甲基-1,6-双溴化三甲铵
溴化己烷双铵
溴化六亚甲基双三甲铵
HEXAMETHONIUM DIBROMIDE
HEXAMETHYLENEBIS(TRIMETHYLAMMONIUM BROMIDE)
HEXANE-1,6-BIS(TRIMETHYLAMMONIUM BROMIDE)
N,N,N,N',N',N'-HEXAMETHYLHEXAMETHYLENEDIAMMONIUM DIBROMIDE
6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dibromide
alpha,omega-bis(trimethylammonium)hexanedibromide
esametina
gangliostat
hexamethioniumbromide
hexamethylenebis(trimethyl-ammoniudibromide
hexameton
hexoniumdibromide
simpatoblock
vegolysen
vegolysin
Hexane-1,6-bis(trimethylammonium bromide), N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dibromide
Hexamethonium bromide ,98%
HEXAMETHONIUM BROMIDE HYDRATE, 98+%
Methobromine
物理化学性质
知名试剂公司产品信息
Hexamethonium Bromide,>98.0%(T)(55-97-0)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-B0569 | 溴化六甲铵 Hexamethonium Bromide | 55-97-0 | 500mg | 400元 |
| 2024/01/25 | HY-B0569 | 溴化六甲铵 Hexamethonium Bromide | 55-97-0 | 10mM * 1mLin DMSO | 500元 |
| 2024/01/25 | HY-B0569 | 溴化六甲铵 Hexamethonium Bromide | 55-97-0 | 1g | 500元 |
常见问题列表
| Target | Value |
| Dopamine subtype 2 receptor | |
| AChR |
Hexamethonium Bromide能有效抵抗Ach和卡巴胆碱(CCh)对大鼠肩胛舌骨肌终板振幅的响应，EC50分别为300 μM和100 μM。0.6 μM 筒箭毒碱存在下，Hexamethonium Bromide (50-200 μM)使神经诱发的终板电流(e.p.cs)的振幅增加。在大鼠肌肉匀浆中，Hexamethonium Bromide也是乙酰胆碱酯酶活性的弱抑制剂，EC50为1.5 mM。在大鼠一侧膈肌中，Hexamethonium Bromide (200 μM)降低终板电流(e.p.cs) (降低~25%)和微终板电流(m.e.p.cs) (降低~20%)衰变的时间常数。在低频刺激(0.5-2 Hz)下，Hexamethonium Bromide (200 μM)增加30-40% e.p.c.量子含量。
Hexamethonium Bromide (0.2-25 mg/kg; i.v.) significantly reduces the renal sympathetic nerve activity (RSNA), mean arterial pressure (MAP) and heart rate (HR) in the Wistar rats and the spontaneously hypertensive rats (SHRs).
Hexamethonium Bromide (0.2-1.0 mg/kg; i.v.) treatments show no significant differences in the RSNA, MAP or HR between Wistar rats and SHRs.
Hexamethonium Bromide (5.0-25 mg/kg; i.v.) results in a greater reduction in the RSNA and MAP in SHRs compared with Wistar rats.
| Animal Model: | Male normotensive Wistar rats (280-320 g), SHRs |
| Dosage: | 0.2 mg/kg, 1.0 mg/kg, 5.0 mg/kg, 25 mg/kg |
| Administration: | Intravenous injection |
| Result: | Significantly reduced the RSNA, MAP and HR in the Wistar rats and the SHRs. |