550997-55-2
550997-55-2 结构式
基本信息
中文别名
化合物 T11222 英文别名
ERB-196WAY-202196
1-Naphthalenecarbonitrile, 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxy-
物理化学性质
沸点497.0±45.0 °C(Predicted)
密度1.45±0.1 g/cm3(Predicted)
酸度系数(pKa)8.10±0.20(Predicted)
形态Solid
颜色Light brown to brown
550997-55-2价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/12/22 | HY-19468 | ERB-196 | 550997-55-2 | 1 mg | 1280元 |
| 2025/12/22 | HY-19468 | ERB-196 | 550997-55-2 | 5 mg | 3220元 |
| 2025/12/22 | HY-19468 | ERB-196 | 550997-55-2 | 10 mg | 5180元 |
常见问题列表
生物活性
ERB-196 是一个非类固醇选择性雌激素受体-β (ERβ) 激动剂。靶点
ERβ
体内研究
ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control; p<0.05). The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06). The administration of ERB-196 is highly effective in the prevention of lethality. Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control.