66054-36-2
中文名称
Tunicamycin A
英文名称
Tunicamycin A
CAS
66054-36-2
分子式
C38H62N4O16
分子量
830.93
MOL 文件
66054-36-2.mol
66054-36-2 结构式
基本信息
中文别名
衣霉素V 英文别名
Tunicamycin VTunicamycin A
2,4(1H,3H)-Pyrimidinedione, 1-[(11S)-11-O-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]-6,10-dideoxy-10-[[(2E)-13-methyl-1-oxo-2-tetradecenyl]amino]-L-galacto-β-D-allo-undecodialdo-1,4-furanose-11,7-pyranos-1-yl]-
物理化学性质
密度1.41±0.1 g/cm3(Predicted)
储存条件-20°C
溶解度Soluble in DMSO
酸度系数(pKa)9.39±0.10(Predicted)
形态Solid
颜色White to off-white
Tunicamycin A价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/09/15 | HY-N8395 | Tunicamycin A Tunicamycin V | 66054-36-2 | 1mg | 9300元 |
常见问题列表
生物活性
Tunicamycin V (Tunicamycin A) 是一种核苷天然产物，可抑制细菌 phospho-N-acetylmuramyl-pentapeptide transferase (MraY)，IC50 为 0.35 μM。Tunicamycin V 具有抗菌活性。靶点
IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))
体外研究
Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER).