70-09-7
中文名称
2-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺
英文名称
NSC 38280
CAS
70-09-7
MOL 文件
70-09-7.mol
更新日期
2024/12/15 19:35:15

基本信息
中文别名
化合物NSC-603392-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺
英文别名
WanderHr 2198
Nsc 60339
NSC 38280
2-Chloro-4',4''-di-2-imidazolin-2-yl-terephthalanilide
inhibit,NSC 60339,NSC60339,NSC-60339,Bacterial,Inhibitor
2-Chloro-N,N'-bis[4-(2-imidazolin-2-yl)phenyl]terephthalamide
Terephthalanilide, 2-chloro-4',4''-di-2-imidazolin-2-yl- (8ci)
2-Chloro-N1,N4-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide
1,4-Benzenedicarboxamide, 2-chloro-N,N'-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)- (9ci)
2-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺价格(试剂级)
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2025/02/05 | HY-119172 | 2-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺 NSC-60339 | 70-09-7 | 1 mg | 803元 |
2025/02/05 | HY-119172 | 2-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺 NSC-60339 | 70-09-7 | 5mg | 1988元 |
2025/02/05 | HY-119172 | 2-氯-N1,N4-双(4-(4,5-二氢-1H-咪唑-2-基)苯基)对苯二甲酰胺 NSC-60339 | 70-09-7 | 10mg | 2913元 |
常见问题列表
生物活性
NSC-60339 是外排泵的抑制剂和 AcrAB-TolC 的底物,是聚对苯二甲酸衍生物,是一种潜在的癌症化疗化合物。体外研究
NSC 60339 has been correlated with the sensitivity, resistance, or cross-resistance of 7 tumor lines to phthalanilide treatment in vivo. The sensitive tumors (L1210, L1210/MTX, L1210/ara-C, and P815) rapidly takes up the drug and retained it primarily as lipid-bound drug for the 24-hr experimental period. The resistant tumor, L1210/NSC 60339, and 2 cross-resistant tumors, P388/VCR and P815/VLB, took up as much drug as the sensitive tumors did by 0.5 hr, but there was an efflux of lipid-bound drug from these resistant tumors by 24 hr.