71827-03-7
中文名称
伊维菌素 B1A
英文名称
Avermectin A1a, 5-O-demethyl-22,23-dihydro-
CAS
71827-03-7
分子式
C48H74O14
分子量
875.09
MOL 文件
71827-03-7.mol
更新日期
2025/04/30 17:28:46
71827-03-7 结构式
基本信息
中文别名
伊维菌素杂质1依维菌素B1A
英文别名
Ivermectin B1aIvermectinH2B1a
Ivermectin B1a (>85%)
Ivermectin Impurity 3
Dihydroavermectin B1a
5-O-Demethyl-22,23-dihydroavermectin A1a
22,23-Dihydro-5-O-demethylavermectin A1a
Avermectin A1a, 5-O-demethyl-22,23-dihydro-
(2Ae,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17ar,20R,20ar,20bs)-20,20B-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17A,20,20A,20B-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-L-arabino-hexopyranosyl)-3-o-methyl-alpha-L-arabino-hexopyranoside
物理化学性质
熔点155-157°
沸点717.97°C (rough estimate)
密度1.0683 (rough estimate)
折射率1.6130 (estimate)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)12.42±0.70(Predicted)
形态固体
颜色白色
伊维菌素 B1A价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-126937 | 伊维菌素 B1A Ivermectin B1a | 71827-03-7 | 1 mg | 1500元 |
| 2025/02/08 | HY-126937 | 伊维菌素 B1A Ivermectin B1a | 71827-03-7 | 5mg | 3750元 |
| 2025/02/08 | HY-126937 | 伊维菌素 B1A Ivermectin B1a | 71827-03-7 | 10 mM * 1 mLin DMSO | 7219元 |
常见问题列表
生物活性
Ivermectin B1a 是 Avermectin B1a (HY-15308) 的衍生物，是 Ivermectin (HY-15310) 的主要成分。Ivermectin (MK-933) 是一种广谱抗寄生虫剂。Ivermectin 是应用于抗 SARS-CoV-2/COVID-19 的候选药物。体外研究
Ivermectin belongs to the macrocyclic lactone class of avermectins and consists of a mixture of two homologous compounds, ivermectin B1a (not less than 80%) and ivermectin B1b (not more than 20%). Ivermectin B1a, the major component of Ivermectin, is inactive at a concentration of 0.3 μg/ml, whereas in the case of the minor component, ivermectin B1b, the same concentration produces 100% mortality of snails.