787634-60-0
中文名称
1-Hexanol, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)thio]-
英文名称
1-Hexanol, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)thio]-
CAS
787634-60-0
分子式
C12H15N3O4S
分子量
297.33
MOL 文件
787634-60-0.mol
787634-60-0 结构式
基本信息
中文别名
TQP1017化合物NBDHEX
英文别名
1-Hexanol, 6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)thio]-6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol
应用领域
用途一
NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. It induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors.