80486-69-7
中文名称
氯硫卡松丙酸酯
英文名称
Cloticasone propionate
CAS
80486-69-7
分子式
C25H31ClF2O5S
分子量
517.025
MOL 文件
80486-69-7.mol
更新日期
2025/09/02 16:39:23
80486-69-7 结构式
基本信息
中文别名
氯硫卡松丙酸酯氟替卡松氯丙酸
丙酸氟替卡松杂质L
英文别名
Chloro Fluticasone PropionateFluticasone Chloropropionic acid
Fluticasone propionate Impurity L
5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate
Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(chloromethyl) ester, (6α,11β,16α,17α)-
Chloro Fluticasone Propionate/(6α.,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Chloromethyl) Ester
所属类别
医药中间体：杂环化合物物理化学性质
沸点583.9±50.0 °C(Predicted)
密度1.34±0.1 g/cm3(Predicted)
溶解度Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
酸度系数(pKa)12.53±0.70(Predicted)
形态Solid
颜色White to Off-White
InChIKeyMVLBCBPGBUAVJQ-KENGUEFRNA-N
SMILESO([C@@]1([C@@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)SCCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|