886230-75-7
中文名称
(E)-6-硝基-3-[2-(吡啶-2-基)乙烯基]-1-(四氢-2H-吡喃-2-基)-1H-吲唑
英文名称
(E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS
886230-75-7
分子式
C19H18N4O3
分子量
350.37
MOL 文件
886230-75-7.mol
更新日期
2025/11/10 11:43:02
886230-75-7 结构式
基本信息
中文别名
阿昔替尼中间体 2(E)-6-硝基-3-[2-(吡啶-2-基)乙烯基]-1-(四氢-2H-吡喃-2-基)-1H
(E)-6-硝基-3-[2-(吡啶-2-基)乙烯基]-1-(四氢-2H-吡喃-2-基)-1H-吲唑
英文别名
Axitinib Impurity 54Axitinib Intermediate 2
(E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran...
6-nitro-3-[(E)-2-(2-pyridyl)vinyl]-1-tetrahydropyran-2-yl-indazol e
(E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)
6-nitro-3-(E)-2-pyridin-2-yl-vinyl)-1- (tetrahydropyran-2-yl)-1H-indazole
(E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
(E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
1H-Indazole, 6-nitro-3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-
所属类别
医药中间体：原料药中间体物理化学性质
沸点570.9±50.0 °C(Predicted)
密度1.36
储存条件Sealed in dry,2-8°C
酸度系数(pKa)4.20±0.10(Predicted)
InChIInChI=1S/C19H18N4O3/c24-23(25)15-8-9-16-17(10-7-14-5-1-3-11-20-14)21-22(18(16)13-15)19-6-2-4-12-26-19/h1,3,5,7-11,13,19H,2,4,6,12H2/b10-7+
InChIKeyBKXMYFOISYYOLE-JXMROGBWSA-N
SMILESN1(C2OCCCC2)C2=C(C=CC([N+]([O-])=O)=C2)C(/C=C/C2=NC=CC=C2)=N1