158836-71-6
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- CAS号:
- 158836-71-6
- 英文名:
- nitroflurbiprofen
- 英文别名:
- HCT 1206;nitroflurbiprofen;Nitroxybutyl flurbiprofen;Cyclooxygenase,Inhibitor,COX,Nitroflurbiprofen,HCT-1206,inhibit,HCT1206;[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 4-(nitrooxy)butyl ester
- 中文名:
- 158836-71-6
- 中文别名:
- 硝基氟比洛芬;化合物 T16329;硝基氟比洛芬(氟比洛芬杂质31)
- CBNumber:
- CB21392461
- 分子式:
- C19H20FNO5
- 分子量:
- 361.36
- MOL File:
- 158836-71-6.mol
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158836-71-6化学性质
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沸点:
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468.8±45.0 °C(Predicted)
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密度:
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1.214±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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158836-71-6性质、用途与生产工艺
Nitroflurbiprofen 是一种环氧合酶 (COX) 抑制剂。
In vivo hemodynamic measurements (n = 8/condition) and evaluation of the increased intrahepatic resistance by in situ perfusion (n=5/condition) are performed in rats with thioacetamide-induced cirrhosis that receive either Nitroflurbiprofen (45 mg/kg), Flurbiprofen (30 mg/kg, equimolar concentration to Nitroflurbiprofen), or vehicle by intraperitoneal injection 24 hours and 1 hour prior to the measurements. Treatment with Nitroflurbiprofen, an NO-releasing cyclooxygenase inhibitor, improves portal hypertension without major adverse effects in thioacetamide-induced cirrhotic rats by attenuating intrahepatic vascular resistance, endothelial dysfunction, and hepatic hyperreactivity to vasoconstrictors.
158836-71-6
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-U00013 | 158836-71-6
Nitroflurbiprofen | 158836-71-6 | 1mg | 1800元 |
| 2024/01/25 | HY-U00013 | 158836-71-6
Nitroflurbiprofen | 158836-71-6 | 5mg | 3800元 |
158836-71-6, 158836-71-6 相关搜索:
- C19H20FNO5
- 硝基氟比洛芬(氟比洛芬杂质31)
- 化合物 T16329
- 硝基氟比洛芬
- 158836-71-6
- Cyclooxygenase,Inhibitor,COX,Nitroflurbiprofen,HCT-1206,inhibit,HCT1206
- [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 4-(nitrooxy)butyl ester
- Nitroxybutyl flurbiprofen
- HCT 1206
- nitroflurbiprofen