盐酸双环维林
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- CAS号:
- 67-92-5
- 英文名:
- DICYCLOMINE HYDROCHLORIDE
- 英文别名:
- DICYCLOMINE HCL;Dicycloverine HCl;dyspas;atumin;Bentyl);mamiesan;oxityl-p;merbentyl;Magesan P;bentomine
- 中文名:
- 盐酸双环维林
- 中文别名:
- 盐酸双环胺;盐酸双环维林;双环胺盐酸盐;盐酸二环甘氨酸;盐酸双环维林杂质;双环维林盐酸盐[受控];盐酸双环维林 EP标准品;盐酸双环维林 USP标准品;盐酸双环胺DICYCLOVERINE HYDROCHLORIDE;DICYCLOVERINE HCL (DICYCLOMINE HCL)
- CBNumber:
- CB2285591
- 分子式:
- C19H36ClNO2
- 分子量:
- 345.95
- MOL File:
- 67-92-5.mol
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盐酸双环维林性质、用途与生产工艺
Dicyclomine hydrochloride 是一种有效的口服活性毒蕈碱胆碱能受体 (muscarinic cholinergic receptors) 拮抗剂。Dicyclomine hydrochloride 对 M1 受体亚型 (Ki=5.1 nM) 和 M2 受体亚型 (Ki=54.6 nM) 在刷缘膜和基底质膜中均表现出较高的亲和力。Dicyclomine hydrochloride是一种抗痉挛试剂，在体内可缓解胃肠道平滑肌痉挛。
Ki: 5.1 nM (muscarinic M1 receptor subtype in brush-border membrane)Ki: 54.6 nM (muscarinic M2 receptor subtype in basal plasma membrane
Dicyclomine hydrochloride (intraperitoneal injection; 8 mg/kg; daily) exacerbates the cognitive impairments in all the measurements. In addition, the memory impairments are worse in dicyclomine-treated 3xTg-AD mice compared to dicyclomine-treated NonTg mice.Dicyclomine hydrochloride (intraperitoneal injection; 2.0, 4.0, and 8.0 mg/kg; 7 days) produces a highly significant effect on performance in the paired-associates learning (PAL) task in mice.And systemic treatment at lower doses show behavioral impairments in mice in spatial tasks.
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Animal Model:
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C57Bl/6 mice
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Dosage:
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2.0, 4.0, and 8.0 mg/kg
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Administration:
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Intraperitoneal injection; daily; 7 days
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Result:
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Produced impairments due to actions of the agent outside of the hippocampus.
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类别
有毒物品
毒性分级
中毒
急性毒性
口服-大鼠 LD50: 625 毫克/公斤; 口服-小鼠 LD50: 625 毫克/公斤
可燃性危险特性
可燃;燃烧产生有毒氮氧化物和氯化氢烟雾;病人用药副作用;僵硬,呼吸困难,苍白
储运特性
通风低温干燥
灭火剂
干粉,泡沫,沙土,二氧化碳, 雾状水
盐酸双环维林
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-B1339 | 盐酸双环维林
Dicyclomine hydrochloride | 67-92-5 | 100mg | 242元 |
| 2024/01/25 | HY-B1339 | 盐酸双环维林
Dicyclomine hydrochloride | 67-92-5 | 10mM * 1mLin DMSO | 266元 |
盐酸双环维林
生产厂家
全球有 104家供应商
盐酸双环维林国内生产厂家
67-92-5, 盐酸双环维林 相关搜索:
- BENTYL
- Pharmaceuticals
- Intermediates & Fine Chemicals
- 药靶配体
- 医药原料
- 标准品
- 中药对照品
- 小分子抑制剂
- 34595
- C19H36ClNO2
- C19H35NO2HCl
- 盐酸二环甘氨酸
- 盐酸双环维林 EP标准品
- DICYCLOVERINE HCL (DICYCLOMINE HCL)
- 盐酸双环维林 USP标准品
- 双环胺盐酸盐
- 盐酸双环胺DICYCLOVERINE HYDROCHLORIDE
- 双环维林盐酸盐[受控]
- 盐酸双环维林杂质
- 盐酸双环维林
- 盐酸双环胺
- 67-92-5
- DICYCLOMINE HCL IP/BP/USP
- DICYCLOMINE HCl IP
- IBS,syndrome,Dicyclomine hydrochloride,Dicyclomine,Dicycloverine,antispasmodic,Alzheimer’s disease,irritable,Inhibitor,anticholinergic,Bacterium,inhibit,mAChR,bowel,Muscarinic acetylcholine receptor
- Dicycloverine HCl
- DICYCLOMINE HCL
- Dicycloverine HCl (Dicyclomine HCl)
- Dicycloverine hydrochloride CRS
- icyclominehydrochloride
- Dicyclomine HydrochlorideQ: What is
Dicyclomine Hydrochloride Q: What is the CAS Number of
Dicyclomine Hydrochloride Q: What is the storage condition of
Dicyclomine Hydrochloride Q: What are the applications of
Dicyclomine Hydrochloride
- Dicycloverine hydrochloride (D1060000)
- Dicyclomine Hydrochloride (1191000)
- Dicycloverine for system suitability (Y0001864)
- beta-diethylaminoethyl-1-cyclohexylhexahydrobenzoatehydrochloride
- beta-diethylaminoethyl1-cyclohexylcyclohexanecarboxylatehydrochloride
- bentylolhydrochloride
- bentylhydrochloride
- bentomine
- DicycloMine Hydr
- Dicyclomine Hydrochloride (125 mg)
- 2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride
- atumin
- 2-(diethylamino)ethyl(bicyclohexyl)-1-carboxylatehydrochloride
- 1-cyclohexyl-cyclohexan-1-carbonsaeure-2-diaethylaminoaethylesterhydrochlori
- DICYCLOMINEHYDROCHLORIDE,USP
- Magesan P
- 2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride
- sancarbossilico
- procyclomin
- oxityl-p
- merbentyl
- mamiesan
- kolantylhydrochloride
- dyspas
- di-syntramine
- diocylhydrochloride
- diethylaminocarbethoxybicyclohexylhydrochloride