4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
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- CAS号:
- 23307-72-4
- 英文名:
- sodium N-(6-chloropyrazinyl)sulphanilamidate
- 英文别名:
- Sulfaclozine (sodium salt);Sulfaclozine sodium monohydrate;sodium N-(6-chloropyrazinyl)sulphanilamidate;Sodium ((4-aminophenyl)sulfonyl)(6-chloropyrazin-2-yl)amide;4-Amino-N-(6-chloro-2-pyrazinyl)benzenesulfonamide sodium salt
- 中文名:
- 4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
- 中文别名:
- 4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐;((4-氨基苯基)磺酰基)(6-氯吡嗪-2-基)酰胺钠
- CBNumber:
- CB3921924
- 分子式:
- C10H10ClN4NaO2S
- 分子量:
- 308.72
- MOL File:
- 23307-72-4.mol
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4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐化学性质
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储存条件:
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under inert gas (nitrogen or Argon) at 2–8 °C
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溶解度:
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DMF: 1 mg/ml; DMSO: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
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4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐性质、用途与生产工艺
Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物，具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病，禽霍乱和球虫病)的相关研究。
The elimination of Sulfaclozine in the three systems: UV/TiO
2
, UV/K
2
S
2
O
8
, and UV/TiO
2
/K
2
S
2
O
8
. Sulfaclozine is weakly adsorbed on the surface of TiO
2
at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO
2
, UV/K
2
S
2
O
8
, and UV/TiO
2
/K
2
S
2
O
8
in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of
•
OH and SO
4
•−
radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals.
Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections.
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Animal Model:
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14 male broiler chickens (30-day-old)
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Dosage:
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60 mg/kg
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Administration:
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Intravenous injection or oral administration (Pharmacokinetic Analysis)
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Result:
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Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively.
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4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
上下游产品信息
上游原料
下游产品
4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
生产厂家
23307-72-4, 4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐 相关搜索:
- ((4-氨基苯基)磺酰基)(6-氯吡嗪-2-基)酰胺钠
- 4-氨基-N-(6-氯-2-吡嗪基)苯磺酰胺钠盐
- 23307-72-4
- Sulfaclozine (sodium salt)
- Sodium ((4-aminophenyl)sulfonyl)(6-chloropyrazin-2-yl)amide
- 4-Amino-N-(6-chloro-2-pyrazinyl)benzenesulfonamide sodium salt
- Sulfaclozine sodium monohydrate
- sodium N-(6-chloropyrazinyl)sulphanilamidate