福罗帕泛
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- CAS号:
- 136468-36-5
- 英文名:
- Foropafant
- 英文别名:
- SR 27417;Foropafant;Faropafant;SR 27417 >=98% (HPLC);inhibit,SR-27417,SR 27417,Foropafant,Inhibitor;N-(2-Dimethylaminoethyl)-N-(3-pyridylmethyl)-4-(2,4,6-triisopropylphenyl)thiazol-2-amine;4-(2,4,6-Triisopropylphenyl)-N-[2-(dimethylamino)ethyl]-N-(3-pyridylmethyl)thiazol-2-amine;N1,N1-Dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2;N1,N1-Dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2-di;N1,N1-dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2-diamine
- 中文名:
- 福罗帕泛
- 中文别名:
- 福罗帕泛;福罗帕泛(抗凝药);化合物 T15338
- CBNumber:
- CB41117105
- 分子式:
- C28H40N4S
- 分子量:
- 464.71
- MOL File:
- 136468-36-5.mol
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福罗帕泛化学性质
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沸点:
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571.6±60.0 °C(Predicted)
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密度:
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1.065±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,2-8°C
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溶解度:
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DMSO: soluble5mg/mL (clear solution, warmed)
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酸度系数(pKa):
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8.75±0.28(Predicted)
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形态:
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powder
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颜色:
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white to beige
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福罗帕泛性质、用途与生产工艺
Foropafant (SR27417) 是一种高效、竞争性、选择性、可口服的血小板激活因子 (PAF) 受体拮抗剂，抑制 [3H]PAF 与其受体结合，Ki 值为 57 pM，比未被标记的 PAF 低至少 5 倍。Foropafant (SR27417) 有效抑制 PAF 诱导的兔和人血小板聚集。
Ki: 57 pM ([
3
H]PAF binding)
福罗帕泛
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-128694 | Foropafant | | 1 mg | 727元 |
| 2024/01/25 | HY-128694 | 福罗帕泛
Foropafant | 136468-36-5 | 5mg | 1600元 |
136468-36-5, 福罗帕泛 相关搜索:
- 重点产品
- 合成
- C28H40N4S
- 化合物 T15338
- 福罗帕泛
- 福罗帕泛(抗凝药)
- 136468-36-5
- inhibit,SR-27417,SR 27417,Foropafant,Inhibitor
- 1,2-Ethanediamine, N1,N1-dimethyl-N2-(3-pyridinylmethyl)-N2-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-
- SR 27417 >=98% (HPLC)
- N1,N1-Dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2
- N1,N1-Dimethyl-N2-(3-pyridinylmethyl)-N2-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-1,2-ethanediamine
- N,N-Dimethyl-N′-(3-pyridinylmethyl)-N′-[4-[2,4,6-tris(1-methylethyl)phenyl]-2-thiazolyl]-1,2-ethanediamine
- Faropafant
- N1,N1-Dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2-di
- N1,N1-dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2-diamine
- N-(2-Dimethylaminoethyl)-N-(3-pyridylmethyl)-4-(2,4,6-triisopropylphenyl)thiazol-2-amine
- SR 27417
- 4-(2,4,6-Triisopropylphenyl)-N-[2-(dimethylamino)ethyl]-N-(3-pyridylmethyl)thiazol-2-amine
- Foropafant