ASOXIME CHLORIDE
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- CAS号:
- 34433-31-3
- 英文名:
- ASOXIME CHLORIDE
- 英文别名:
- hi6;hj6;hi-6;Transant;wr249655;Ccris 7699;HI 6 Chloride;hi-6dichloride;ASOXIME CHLORIDE;Asoxime dichloride
- 中文名:
- ASOXIME CHLORIDE
- 中文别名:
- 化合物 T14333;化合物ASOXIME DICHLORIDE
- CBNumber:
- CB4137803
- 分子式:
- C14H16Cl2N4O3
- 分子量:
- 359.21
- MOL File:
- 34433-31-3.mol
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ASOXIME CHLORIDE化学性质
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熔点:
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145-147°C
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储存条件:
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-20°C
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溶解度:
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H2O: soluble15mg/mL (clear solution)
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形态:
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powder
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颜色:
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white to beige
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稳定性:
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1-10% Aqueous solution
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ASOXIME CHLORIDE性质、用途与生产工艺
Asoxime dichloride 是乙酰胆碱受体 (AChRs) 拮抗剂，包括烟碱受体，α7 乙酰胆碱受体。Asoxime dichloride 参与调节免疫应答。Asoxime dichloride 可作为抗原使用，改善神经系统的免疫效果。
IC50: acetylcholine receptors (AChRs)
Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg. A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant.
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Animal Model:
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Balb/c mice
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Dosage:
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2% and 0.2% of median lethal dose 15.6 and 1.56mg/kg
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Administration:
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Intramuscular injection into the rear limb
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Result:
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Improved vaccination efficacy at the level of immunity regulation by the nervous system.
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ASOXIME CHLORIDE
上下游产品信息
上游原料
下游产品
34433-31-3, ASOXIME CHLORIDE 相关搜索:
- Heterocycles
- Amines
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Activators
- C14H16N4O32Cl
- 化合物ASOXIME DICHLORIDE
- 化合物 T14333
- 34433-31-3
- Asoxime dichloride
- 1-[(4-Carbamoylpyridinium-1-yl)methoxymethyl]-2-(hydroxyiminomethyl)pyridinium·2chloride
- 1-(4-Carbamoylpyridiniomethoxymethyl)-2-(hydroxyiminomethyl)pyridinium·2chloride
- ASOXIME CHLORIDE
- 1[[[4-(AMINOCARBONYL)PYRIDINIO]METHOXY]METHYL]-2-[(HYDROXYIMINO)METHYL]PYRIDINIUM DICHLORIDE
- wr249655
- pyridinium,4’-carbamoyl-2-formyl-1,1’-(oxydimethylene)di-,dichloride,2-oxime
- pyridinium,4’-carbamoyl-2-formyl-1,1’-(oxydimethylene)di-,dichloride,2-oxi
- pyridinium,1-(((4-(aminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)
- hj6
- Ccris 7699
- 1-(2-Hydroxyiminomethyl-1-pyridino)-3-(4-carbamoyl-1-pyridino)-2-oxapropane dichloride monohydrate
- (((4-(Iminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)pyridinium dichloride
- hi-6dichloride
- hi-6
- hi6
- 4’-carbamoyl-2-formyl-1,1’-(oxydimethylene)di-pyridinium-dichloride-2-oxime
- (((4-(iminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)pyridi
- Transant
- 4-Carbamoyl-1-[[[2-[(hydroxyimino)methyl]pyridinium-1-yl]methoxy]methyl]pyridinium dichloride
- 1-[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium chloride
- HI 6 Chloride