2'',3'',5''-Triacetyl -azacytidine
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- CAS-Nr.
- 10302-78-0
- Englisch Name:
- 2'',3'',5''-Triacetyl -azacytidine
- Synonyma:
- Nsc291930;-O-triacetate;Triacetyl azacitidine;Azacitidine Triacetate;Azacitidine Impurity 48;Intermediate of Azacitidine;2'3'5'-triacetyl-5-Azacytosine;2',3',5'-triacetyl-5-Azacytidine;2',3',5'-Tri-O-Acetyl-Azacytidine;2'',3'',5''-Triacetyl -azacytidine
- CBNumber:
- CB01564248
- Summenformel:
- C14H18N4O8
- Molgewicht:
- 370.31
- MOL-Datei:
- 10302-78-0.mol
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2'',3'',5''-Triacetyl -azacytidine Eigenschaften
- Siedepunkt:
- 497.3±55.0 °C(Predicted)
- Dichte
- 1.60±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- Löslichkeit
- ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
- Aggregatzustand
- crystalline solid
- pka
- 3.06±0.20(Predicted)
- CAS Datenbank
- 10302-78-0
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
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Sicherheit |
P261 |
Einatmen von Staub vermeiden. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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2'',3'',5''-Triacetyl -azacytidine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
5-
Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-
triacetyl-
5-
Azacytidine is a prodrug form of 5-
azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.
Chemische Eigenschaften
White to off-white powder
Verwenden
5-Azacytidine is an inhibitor of DNA methyltransferaes, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.[Cayman Chemical]
2'',3'',5''-Triacetyl -azacytidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2'',3'',5''-Triacetyl -azacytidine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 98)Lieferanten
Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
Henan Fengda Chemical Co., Ltd
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+86-371-86557731 +86-13613820652
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info@fdachem.com |
China |
8174 |
58 |
Henan Tianfu Chemical Co.,Ltd.
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+86-0371-55170693 +86-19937530512
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info@tianfuchem.com |
China |
21691 |
55 |
Hangzhou FandaChem Co.,Ltd.
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008657128800458; +8615858145714
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fandachem@gmail.com |
China |
9348 |
55 |
Antai Fine Chemical Technology Co.,Limited
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18503026267
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info@antaichem.com |
CHINA |
9641 |
58 |
Hubei Ipure Biology Co., Ltd
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+8613367258412
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ada@ipurechemical.com |
China |
10326 |
58 |
Career Henan Chemica Co
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+86-0371-86658258 15093356674;
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laboratory@coreychem.com |
China |
30255 |
58 |
Hefei TNJ Chemical Industry Co.,Ltd.
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0551-65418671
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sales@tnjchem.com |
China |
34572 |
58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED
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86 18062405514 18062405514
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ada@ipurechemical.com |
CHINA |
3465 |
58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD
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86-571-88216897,88216896 13588875226
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sales@hzclap.com |
CHINA |
6313 |
58 |
Shanxi Xuanran Import and Export Trade Co., Ltd.
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+8617735180244
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mike_yan@xuanranglobal.com |
CHINA |
4022 |
58 |
10302-78-0()Verwandte Suche:
- 2'',3'',5''-Triacetyl -azacytidine
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-o-acetyl-.beta.-D-ribofuranosyl)-
- Nsc291930
- S-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-, triacetate (ester)
- 2',3',5'-triacetyl-5-Azacytidine
- 1,3,5-Triazin-2(1H)-one, 4-aMino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
- Intermediate of Azacitidine
- 2'3'5'-triacetyl-5-Azacytosine
- 2',3',5'-Tri-O-Acetyl-Azacytidine
- Azacitidine Triacetate
- Triacetyl azacitidine
- 2,3,5-tri-O-acetyl-β-D-ribofuranose-4-amino-1,3,5-triazine
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-
- -O-triacetate
- 4-Amino-1-(2,3,5-tri-o-acetyl-beta-d-ribofuranosyl)-1,3,5-triazin-2(1h)-one
- 5-Azacytidine 2’,3’5’-O-triacetate
- 2,3,5-tri-O-acetyl-β-D-ribofuranose-4-amino-1,3,5-triazine
- Azacitidine Impurity 48
- 2'',3'',5''-Triacetyl -azacytidine
- 10302-78-0