Volitinib

1313725-88-0

CAS-Nr.: 1313725-88-0

Englisch Name:: Volitinib

Synonyma:: Savolitinib;HMPL-504;Savolitinib (AZD6094);CS-2676;Volitinib;AZD-6094);EOS-60799;HMPL0-504;Volitinib USP/EP/BP;AZD-6094 (VOLITINIB)

CBNumber:: CB02731160

Summenformel:: C17H15N9

Molgewicht:: 345.36

MOL-Datei:: 1313725-88-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 125

Volitinib Eigenschaften

Schmelzpunkt:: 205-207°C

Dichte: 1.55±0.1 g/cm3(Predicted)

storage temp.: -20°C Freezer

Löslichkeit: DMSO (Slightly), Methanol (Slightly)

pka: 5.67±0.50(Predicted)

Aggregatzustand: Solid

Farbe: Pale Beige

CAS Datenbank: 1313725-88-0

Sicherheit

Volitinib Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.

Verwenden

Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.

Clinical Use

It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.

Volitinib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

N-methoxy-N-methylimidazo[1,2-a]pyridine-6-carboxamide IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID 1-Methyl-4-pyrazole boronic acid pinacol ester 6-Aminonicotinsaeure

Downstream Produkte

Volitinib(enantiomer)

Volitinib Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 125)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29118	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	992	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Hong Kong Tiansheng New Material Trading Co., Ltd	+8617320695765	zxx@hktiansheng.com	China	981	58

AZD6094,Volitinib, HMPL-504, Savolitinib
1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
Volitinib
HMPL-504(AZD6094, Volitinib)
EOS-60799
AZD-6094)
Savolitinib (Volitinib
(S)-1-(1-(imidazo[1,2-a] yridine-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
(S)-1-(1-(IMIDAZO[1,2-A]
HMPL-504; HMPL504; HMPL504; AZD-6094; AZD 6094; AZD6094
Volitinib (Savolitinib, AZD-6094)
CS-2676
VOLITINIB; HMPL504; AZD-6094;VOLITINIB; HMPL-504; AZD6094; HMPL 504; AZD 6094
Savolitinib(AZD6094, HMPL-504)
1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-
Volitinib USP/EP/BP
4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[ 1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyra zole
Savolitinib
HMPL-504
Savolitinib (AZD6094)
Pharmaceutical Intermediate Volitinib
AZD-6094 (VOLITINIB)
VOLITINIB (AZD6094, SAVOLITINIB)
HMPL0-504
1313725-88-0
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