ARM1

68729-05-5

CAS-Nr.: 68729-05-5

Englisch Name:: ARM1

Synonyma:: ARM1;ARM-1 (ARM1);4-(4-Benzylphenyl)-1,3-thiazol-2-amine;2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]-;Epoxide Hydrolase,ARM1,HCT-116 cells,Inhibitor,LTA4H,ARM-1,cytotoxic,positive control,Aminopeptidase,4BSA,inhibit,ARM 1

CBNumber:: CB03152553

Summenformel:: C16H14N2S

Molgewicht:: 266.36

MOL-Datei:: 68729-05-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

ARM1 Eigenschaften

storage temp.: Store at -20°C

Löslichkeit: ≤1mg/ml in ethanol;10mg/ml in DMSO;15mg/ml in dimethyl formamide

Aggregatzustand: crystalline solid

Sicherheit

ARM1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Leukotriene A₄ (LTA₄) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB₄ from LTA₄ and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB₄ synthesis in human neutrophils (IC₅₀ = ~0.5 μM) and conversion of LTA₄ to LTB₄ by purified LTA₄ hydrolase (K_i = 2.3 μM). ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA₄ hydrolase.

Verwenden

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 μM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 μM). ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.[Cayman Chemical]

ARM1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ARM1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9445	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Block Chemical Technology (Shanghai) Co., LTD	021-20432219 13918097649	li_jinfei@acblock-lab.com	China	9562	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973 13515979683	sales@jamxmpharmatech.com	China	1079	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39997	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 17801761073	Gsiyu@solarbio.com	China	50471	58

ARM1
4-(4-Benzylphenyl)-1,3-thiazol-2-amine
ARM-1 (ARM1)
2-Thiazolamine, 4-[4-(phenylmethyl)phenyl]-
Epoxide Hydrolase,ARM1,HCT-116 cells,Inhibitor,LTA4H,ARM-1,cytotoxic,positive control,Aminopeptidase,4BSA,inhibit,ARM 1
68729-05-5