Anti-Chondroitin Sulfate antibody, Mouse monoclonal

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Struktur
CAS-Nr.
Englisch Name:
Anti-Chondroitin Sulfate antibody, Mouse monoclonal
Synonyma:
Anti-Chondroitin Sulfate antibody, Mouse monoclonal
CBNumber:
CB04669126
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution

Sicherheit

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Monoclonal anti-chondroitin sulfate antibody, (mouse IgM isotype) is derived from the hybridoma CS56 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with Ventral membranes of chicken gizzard fibroblasts. This antibody recognizes chondroitin sulfate containing proteoglycans (CSPG) in bovine mammary gland epithelial (BMGE) cells and also in human, chicken and mouse fibroblasts or tissues.
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) is encoded by the gene mapped to human chromosome 15q24.2-15q24.3. It is a growth-inhibitory chondroitin sulfate proteoglycan (CSPG) produced after spinal cord injury. It has a single glycosaminoglycan (GAG) chain. The protein belongs to the transmembrane chondroitin sulfate proteoglycans family.

Biochem/physiol Actions

Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) stimulates the activation of integrins in dorsal root ganglion neurons. It also has a role in stimulating inflammatory cytokine expression in microglia. CSPG4 plays a vital role in brain repair. Overexpression of the gene leads to developmental delay in patients with trisomy of 15q24-qter. CSPG4 serves as a potential prognostic biomarker and therapeutic target in malignant cancer.

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Anti-Chondroitin Sulfate antibody, Mouse monoclonal Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 1)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

  • Anti-Chondroitin Sulfate antibody, Mouse monoclonal
Copyright 2019 © ChemicalBook. All rights reserved