Anti-Chondroitin Sulfate antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-Chondroitin Sulfate antibody, Mouse monoclonal
Synonyms
Anti-Chondroitin Sulfate antibody, Mouse monoclonal
CBNumber:
CB04669126
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-Chondroitin Sulfate antibody, Mouse monoclonal price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB4200696 Anti-Chondroitin Sulfate antibody, Mouse monoclonal clone CS-56, purified from hybridoma cell culture 25μL $160 2023-06-20 Buy
Sigma-Aldrich SAB4200696 Anti-Chondroitin Sulfate antibody, Mouse monoclonal clone CS-56, purified from hybridoma cell culture 100μL $440 2023-06-20 Buy
Product number Packaging Price Buy
SAB4200696 25μL $160 Buy
SAB4200696 100μL $440 Buy

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Chemical Properties,Uses,Production

General Description

Monoclonal anti-chondroitin sulfate antibody, (mouse IgM isotype) is derived from the hybridoma CS56 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with Ventral membranes of chicken gizzard fibroblasts. This antibody recognizes chondroitin sulfate containing proteoglycans (CSPG) in bovine mammary gland epithelial (BMGE) cells and also in human, chicken and mouse fibroblasts or tissues.
Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) is encoded by the gene mapped to human chromosome 15q24.2-15q24.3. It is a growth-inhibitory chondroitin sulfate proteoglycan (CSPG) produced after spinal cord injury. It has a single glycosaminoglycan (GAG) chain. The protein belongs to the transmembrane chondroitin sulfate proteoglycans family.

Biochem/physiol Actions

Chondroitin sulfate proteoglycan 4 (CSPG4) or nerve/glial antigen 2 (NG2) stimulates the activation of integrins in dorsal root ganglion neurons. It also has a role in stimulating inflammatory cytokine expression in microglia. CSPG4 plays a vital role in brain repair. Overexpression of the gene leads to developmental delay in patients with trisomy of 15q24-qter. CSPG4 serves as a potential prognostic biomarker and therapeutic target in malignant cancer.

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-Chondroitin Sulfate antibody, Mouse monoclonal Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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Anti-Chondroitin Sulfate antibody, Mouse monoclonal