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CGP 55845 Produkt Beschreibung

CGP 55845 Struktur
149184-22-5
CAS-Nr.
149184-22-5
Englisch Name:
CGP 55845
Synonyma:
CGP 55845;CGP 55845 hydrochloride;benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;(2S)-3-[[(1S)-1-(3,4-DICHLOROPHENYL)ETHYL]AMINO-2-HYDROXYPROPYL](PHENYLMETHYL)PHOSPHINIC ACID;(2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinicacidhydrochloride
CBNumber:
CB0718390
Summenformel:
C18H22Cl2NO3P
Molgewicht:
402.25
MOL-Datei:
149184-22-5.mol

CGP 55845 Eigenschaften

storage temp. 
Store at RT
Löslichkeit
DMSO: soluble5mg/mL, clear (warmed)
Aggregatzustand
powder
Farbe
white to beige

Sicherheit

WGK Germany  3
RTECS-Nr. SZ4680000

CGP 55845 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivität

Potent, selective GABA B receptor antagonist (IC 50 = 5 nM) that prevents agonist binding (pK i = 8.35) and inhibits GABA and glutamate release (pEC 50 values are 8.08 and 7.85 respectively). Inhibits GABA B responses to baclofen (IC 50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro .

CGP 55845 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CGP 55845 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 14)Lieferanten
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candy@biochempartner.com China 5000 62
BOC Sciences 1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 10000 58
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  • CGP 55845
  • (2S)-3-[[(1S)-1-(3,4-DICHLOROPHENYL)ETHYL]AMINO-2-HYDROXYPROPYL](PHENYLMETHYL)PHOSPHINIC ACID
  • (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinicacidhydrochloride
  • CGP 55845 hydrochloride
  • benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid
  • 149184-22-5
  • C18H22Cl2NO3PHCl
  • C18H23Cl3NO3P
  • GABA/Glycine receptor
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