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Fungichromin

Fungichromin Struktur
6834-98-6
CAS-Nr.
6834-98-6
Bezeichnung:
Fungichromin
Englisch Name:
Fungichromin
Synonyma:
Lagosin;Cogomycin;Fungichromin;Lagosin【antibiotic】;(3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one;Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-
CBNumber:
CB0904201
Summenformel:
C35H58O12
Molgewicht:
670.83
MOL-Datei:
6834-98-6.mol
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Fungichromin Eigenschaften

Schmelzpunkt:
157-162° (dec)
alpha 
D20 -227.7° (c = 0.53 in DMF)
Siedepunkt:
914.0±65.0 °C(Predicted)
Dichte
1.196±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
Soluble in DMSO
Aggregatzustand
solid
pka
12.77±0.70(Predicted)
Farbe
Light yellow to yellow

Sicherheit

Toxizität LD50 in mice (mg/kg): 1624 orally; 33.3 i.p. (Umezawa, Tanaka)

Fungichromin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Lagosin is a pentaene antifungal produced by Streptomyces, first isolated in 1958 by researchers at MIT in the USA. The discovery was soon followed by several independent isolations as lagosin and cogomyin. Initially these metabolites were thought to be isomeric, but Pandey and colleagues at NCI definitively demonstrated they were identical. Structurally, lagosin is 14-hydroxyfilipin III and the most polar member of the filipin family of fungicides. Lagosin exhibits broad spectrum antifungal and antitumor activity and, like filipin, acts via interaction with cell membrane sterols.

Fungichromin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fungichromin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 35)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739
 info@dycnchem.com China 53899 58
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310
 526763801@qq.com China 9261 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9803 58
Raw material medicin reagent co.,Ltd
sales@njromanme.com China 4529 58
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Shanghai Linka Biotechnology Co., Ltd. 18301977208
2126935757@qq.com China 214 55
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58

6834-98-6(Fungichromin)Verwandte Suche:

Fungichromin
  • Lagosin
  • Fungichromin
  • Cogomycin
  • Lagosin【antibiotic】
  • Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-
  • (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one
  • 6834-98-6
  • C35H58O12
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