Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat)

Evans Blue Struktur
314-13-6
CAS-Nr.
314-13-6
Bezeichnung:
Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat)
Englisch Name:
Evans Blue
Synonyma:
t1824;evablin;CI 23860;C.I.24075;DiazoBlue;blue Evan;Evans Blu;diazobleu;Evens Blue;EVANS BLUE
CBNumber:
CB1161546
Summenformel:
C34H29N6NaO14S4
Molgewicht:
896.86
MOL-Datei:
314-13-6.mol

Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat) Eigenschaften

storage temp. 
Store at RT.
Löslichkeit
DMSO (Slightly), Water (Slightly)
Colour Index 
23860
Aggregatzustand
Powder/Solid
Farbe
Dark Brown
Wasserlöslichkeit
280 g/L (20 ºC)
Merck 
14,3905
Stabilität:
Stable. Incompatible with strong reducing agents, strong oxidizing agents.
CAS Datenbank
314-13-6
IARC
3 (Vol. 8, Sup 7) 1987
EPA chemische Informationen
C.I. Direct Blue 53 (314-13-6)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T,F
R-Sätze: 45-63-11-61-20/21/22
S-Sätze: 53-45-36/37-16-36/37/39
WGK Germany  3
RTECS-Nr. QJ6440000
TSCA  Yes
HS Code  32129000
Toxizität LD50 intraperitoneal in mouse: 340mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H350 Kann Krebs verursachen. Karzinogenität Kategorie 1A Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R45:Kann Krebs erzeugen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R11:Leichtentzündlich.
R61:Kann das Kind im Mutterleib schädigen.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

Evans Blue is a blue crystal with a green metallic luster. It is very soluble in water, slightly soluble in ethanol, and almost insoluble in benzene, chloroform, and ether. It is soluble in acids and alkalis. It is hygroscopic, inducing moisture. It changes color when the pH is close to 10.

Definition

ChEBI: Evans blue is an organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence. It has a role as a histological dye, a fluorochrome, a teratogenic agent and a sodium channel blocker. It contains an Evans blue(4-).

synthetische

3,3′-Dimethylbenzidine double nitriding, in alkaline conditions and 4-Amino-5-hydroxynaphthalene-1,3-disulfonic acid (2 Moore) coupled.

Allgemeine Beschreibung

Blue crystals with a greenish-bronze luster or a black powder.

Air & Water Reaktionen

Azo dyes can be explosive when suspended in air at specific concentrations. Soluble in water.

Reaktivität anzeigen

Direct Blue 53 is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Direct Blue 53 can react with strong reducing and oxidizing agents.

Brandgefahr

Flash point data for Direct Blue 53 are unavailable; however, Direct Blue 53 is probably combustible.

Biologische Aktivität

Potent inhibitor of L-glutamate uptake into synaptic vesicles. Also inhibits AMPA and kainate receptor-mediated currents (IC 50 values are 220 and 150 nM respectively). P2X-selective purinoceptor antagonist.

Sicherheitsprofil

Poison by intraperitoneal route.Moderately toxic by intravenous route. An experimentalteratogen. Other experimental reproductive effects.Questionable carcinogen with experimental tumorigenicdata. Mutation data reported. When heated todecomposition it

Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 286)Lieferanten
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314-13-6(Tetranatrium-6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalindisulfonat))Verwandte Suche:


  • EVANS BLUE C.I. No 23860
  • EvansBlue,99%
  • DiazoBlue
  • 1,3-Naphthalenedisulfonic acid, 6,6-(3,3-dimethyl1,1-biphenyl-4,4-diyl)bis(azo)bis4-amino-5-hydroxy-, tetrasodium salt
  • 4,4'-Bis[7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo]-3,3'-bitolyl tetrasodium salt
  • 6,6'-[(3,3'-Dimethyl-4,4'-biphenylylene)bis(azo)]bis[4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid] tetrasodium salt
  • 6,6'-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis(4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid disodium)
  • 3-[[4'-[(4-Amino-2-methyl-5-methoxyphenyl)azo]-3,3'-dimethoxy-1,1'-biphenyl-4-yl]azo]-4-hydroxynaphthalene-1,5-disulfonic acid disodium salt
  • C.I.24075
  • 6,6-([(3,3'-DIMETHYL)-1,1'-BIPHENYL]-4,4'-DIYL)BIS(AZO)BIS[4-AMINO-5-HYDROXY-1,3-NAPHTHALENEDISULPHONIC ACID] TETRASODIUM SALT
  • EVANS BLUE TETR
  • Evans Blue,Direct Blue 53
  • EVANS BLUE COUNTERSTAIN
  • EVANS BLUE, FOR MICROSCOPY
  • blue Evan
  • evans blue (C.I. 23860)
  • evans blue fluka
  • Evens Blue
  • tetrasodium 6,6-((3,3-dimethyl-(1,1-biphenyl-4,4diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalenedisulphonate)
  • tetrasodium 6,6'-((3,3'-dimethyl-(1,1'-biphenyl-4,4'diyl)bis(azo)bis(4-amino-5-hydroxy-1,3-naphthalenedisulphonate)
  • Evans Blue 5GR
  • EVANS BLUE
  • EVAN'S BLUE
  • EVANS BLUE PURE
  • EVANS BLUE TETRASODIUM SALT
  • GEIGY BLUE
  • DIRECT BLUE 53
  • CI NO 23860
  • CI 23860
  • 1,3-naphthalenedisulfonicacid,6,6’-((3,3’-dimethyl-4,4’-biphenylylene)bis(azo
  • 1,3-naphthalenedisulfonicacid,6,6’-[(3,3’-dimethyl[1,1’-biphenyl]-4,4’-diyl)b
  • 1,3-Naphthalenedisulfonicacid,6,6’-[[3,3’-dimethyl(1,1’-biphenyl)-4,4’-diyl]bis(azo)]bis(4-amino-5-hydroxy-,tetrasodiumsalt
  • 4,4’-bis(1-amino-8-hydroxy-2,4-disulfo-7-naphthylazo)-3,3’-bitolyl,tetrasodi
  • 4,4’-bis(1-amino-8-hydroxy-2,4-disulpho-7-naphthylazo)-3,3’-bitolyl,tetrasod
  • 4,4’-bis(7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo)-3,3’-bitolyl,tetrasod
  • 4,4’-bis(7-(1-amino-8-hydroxy-2,4-disulpho)naphthylazo)-3,3’-bitolyl,tetraso
  • 4,4’-bis-[7-(1-Amino-8-hydroxy-2,4-disulpho-naphthyl)azo]-3,3-bitolylsodiumsalt
  • Evans Blu
  • 6,6’-[3,3’-Dimethyl(1,1’-biphenyl)-4,4’-diyl]bis(azo)-bis-[4-amino-5-hydroxy-1,3-naphthale-nedisulfo]
  • azovanblue
  • blekitevansa
  • C.I.DirectBlue5,3-tetrasodiumsalt
  • c.i.directblue53
  • c.i.directblue53,tetrasodiumsalt
  • diamineskyblueff
  • diazobleu
  • diazolpurebluebf
  • directblue53(evan’s
  • directblue53(evan’sblue)
  • dyeevansblue
  • evablin
  • Evans blue, Dye content: &bsim:85%
  • 6,6-([(3,3'-DIMETHYL)-1,1'-BIPHENYL]-4,4'-DIYL)BIS(AZO)BIS[4-AMINO-5-HYDROXY-1,3-NAPHTHALENEDISULPHONIC ACID] TETRASODIUM SALT
  • 3,3'-DITOLYL-4,4'-BIS[7-AZO-1-AMINO-8-NAPHTHOL-2,4-(DISODIUM)DISULFONATE]
  • evansblue,sodiumsalt
  • evansbluedye
  • geigy-blau536
  • geigyblue536,med
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