[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride

[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

LM11A-31 is a p75 neurotrophin receptor (p75^NTR) ligand that inhibits nerve growth factor (NGF) binding to p75^NTR-Fc (A₂ = 1,192 nM). It inhibits DNA damage in and promotes survival of hippocampal neuronal cultures in a p75^NTR- and concentration-dependent manner. LMA11A-31 also inhibits proNGF-induced cell death of mature oligodendrocytes. In vivo, LMA11A-31 (10-100 mg/kg) improves motor function and coordination in the weight-bearing open-field test and nonweight-bearing swim test and increases survival of oligodendrocytes in a mouse model of spinal contusion injury. It prevents and/or reverses atrophy of forebrain cholinergic neurites and cortical dystrophic neurites in Thy-1 hAPP^Lond/Swe and Tg2576 mice with mid- to late stage Alzheimer''s disease. It also reduces excessive alcohol self-administration in rats and decreases huntingtin (Htt) aggregate formation and striatal cholinergic degeneration in the R6/2 mouse model of Huntington''s disease.

Verwenden

(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide is used for the preparation of peptideamides for treatment of retroviral infection.

[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29067	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60

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• (2S,3S)-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Hydrochloride
• [S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride
• (2S,3S)-2-AMINO-3-METHYL-N-(2-MORPHOLIN-4-YLETHYL)PENTANAMIDE
• LM11A-31
• Pentanamide, 2-amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-, hydrochloride (1:2), (2S,3S)-
• LM11A-31 (hydrochloride)
• (2S,3S)-2-Amino-3-methyl-N-(2-morpholinoethyl)pentanamide Dihydrochloride
• LM11A-31 dihydrochloride (LM11A-31 BHS)
• (2S,3S)-2-amino-3-methyl-N-(2-morpholinoethyl)pentanamide hydrochloride
• (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride
• LM11A-31 BHS
• LM11A 31 2HCl
• LM11A-31 D8 dihydrochloride
• [S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride ISO 9001：2015 REACH
• LM11A-31 dihydrochloride salt
• (2S,3S)-2-AMINO-3-
• LM11A-31 HCl
• cholinergic,proNGF,Inhibitor,inhibit,growth,dystrophy,disease,p75,Neurotensin Receptor,LM-11A-31 dihydrochloride,nerve,neurite,receptor,barrier,neurotrophin,LM11A-31,factor,Ligand,LM11A 31 dihydrochloride,blood-brain,LM11A31 dihydrochloride,Alzheimer's,p75NTR
• 1243259-19-9
• Amino Acids & Derivatives
• Chiral Reagents
• Heterocycles
• Intermediates & Fine Chemicals
• Pharmaceuticals
• Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals