ChemicalBook > Produktkatalog >Analytische Chemie >Standard >Pharmazeutische Referenzstandards und Verunreinigungsreferenzstandards >(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

327623-37-0

CAS-Nr.: 327623-37-0

Englisch Name:: (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

Synonyma:: Aprepitant Impurity 1;Aprepitant Impurity 11;Fosaprepitant Impurity 30;Aprepitant M2 Metabolite Enantiomer;Aprepitant Impurity 1 Hydrochloride;Aprepitant Impurity 10 Hydrochloride;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1’Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

CBNumber:: CB12657010

Summenformel:: C20H18F7NO2

Molgewicht:: 437.35

MOL-Datei:: 327623-37-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 41

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Eigenschaften

Siedepunkt:: 387.9±42.0 °C(Predicted)

Dichte: 1.37±0.1 g/cm3(Predicted)

pka: 6.93±0.60(Predicted)

Sicherheit

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 41)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	4973	50
CEG Chemical Science&Technology Co., Ltd.	Mobile:13665161512		China	1785	58
GIHI CHEMICALS CO.,LTD	0086-571-86217390	Sales@gihichem.com	China	861	58
Shanghai Ranxon Chemical Co., Ltd.	13148101715	2073632910@qq.com	China	38	55
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9798	50

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
(2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine
Aprepitant Impurity 1
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant
Aprepitant Impurity 11
Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer
Fosaprepitant Impurity 30
Aprepitant Impurity 1 Hydrochloride
Aprepitant M2 Metabolite Enantiomer
Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-
Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1&rsquo
Aprepitant Impurity 10 Hydrochloride
327623-37-0