Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

1246213-45-5

CAS-Nr.: 1246213-45-5

Englisch Name:: Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

Synonyma:: Ivacaftor Methylcarbonate;N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide;2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate;Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester

CBNumber:: CB12657777

Summenformel:: C26H30N2O5

Molgewicht:: 450.53

MOL-Datei:: 1246213-45-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 19

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Eigenschaften

Siedepunkt:: 583℃

Dichte: 1.198

Flammpunkt:: 306℃

Löslichkeit: Acetone, Dichloromethane, Methanol

Aggregatzustand: Solid

pka: 11.60±0.70(Predicted)

Farbe: Foamy

Sicherheit

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis.

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

5-amino-2,4-di-tert-butylphenyl methyl carbonate 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

Downstream Produkte

Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 19)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai YuLue Chemical Co., Ltd.	021-60345187 13671753212	lzz841106@aliyun.com	China	10287	55
Jinan Putubio Tech Co., Ltd.	+86 (531) 8099-2215	putubio@outlook.com	China	1261	55
Jinan elephant international trading co., LTD		13006575422@163.com	China	6357	58
Dezhou LonWel Pharmaceutical Technology Co., Ltd.	13761310616	39324283@qq.com	China	1946	58
Jinan Yaoyan Pharmaceutical Co., Ltd.		jnyaoyan@163.com	China	3069	58
Shanghai Moss Medicine Technology Co., Ltd.	+86-188369842 +86-15618151133	188369842@qq.com	China	1945	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58