ENNIATIN B

ENNIATIN B Struktur
917-13-5
CAS-Nr.
917-13-5
Englisch Name:
ENNIATIN B
Synonyma:
ENNIATIN B;N-Methylcyclo(L-Val-D-Hmb-N-methyl-L-Val-D-Hmb-N-methyl-L-Val-D-Hmb-);(3S,6R,9S,12R,15S,18R)-3,6,9,12,15,18-Hexaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
CBNumber:
CB1677384
Summenformel:
C33H57N3O9
Molgewicht:
639.83
MOL-Datei:
917-13-5.mol

ENNIATIN B Eigenschaften

storage temp. 
-20°C
Löslichkeit
DMSO: soluble10mg/mL
Aggregatzustand
White to off-white crystalline solid.
Siedepunkt:
827.0±65.0 °C(Predicted)
Dichte
1.036±0.06 g/cm3(Predicted)
Schmelzpunkt:
229 °C
pka
-1.08±0.70(Predicted)

Sicherheit

Kennzeichnung gefährlicher T
R-Sätze: 23/24/25
S-Sätze: 45
RIDADR  2811
WGK Germany  3
HazardClass  6.1(a)
PackingGroup  I
HS Code  29419000

ENNIATIN B Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Enniatins are a family of depsipeptide ionophores, produced several Fusarium species. More recently, the effects of the ennitins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin B is the most studied of four major analogues of the enniatin complex.

Definition

ChEBI: An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine units.

Biochem/physiol Actions

Enniatins are a group of cyclohexadepsipeptide mycotoxins produced by Gnomonia errabuda and several Fusaria species, with phytotoxic, antibiotic, and insecticidal activities. Enniatins function as ionophors by their incorporation into the cellular membrane to form dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. It has been demonstrated that enniatins have a cytotoxic effect on human cancer cells. Furthermore, incubation of H4IIE hepatoma cells with enniatins strongly diminished phosphorylation of the ERK (p44/p42). Enniatins B and B1 inhibit the multi-drug resistance transporter Pdr5p from Saccharomyces cerevisiae, indicating their beneficial potential in cases of drug resistant patients.

ENNIATIN B Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ENNIATIN B Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 95)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
BioBioPha Co., Ltd. 0871-65217109 13211707573;
y.liu@mail.biobiopha.com China 5654 65
TargetMol Chemicals Inc. 021-33632979 15002134094
marketing@targetmol.com China 7934 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632
sales@reading-chemicals.com China 15185 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130
3423497944@qq.com China 8147 55

917-13-5()Verwandte Suche:


  • (3S,6R,9S,12R,15S,18R)-3,6,9,12,15,18-Hexaisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
  • N-Methylcyclo(L-Val-D-Hmb-N-methyl-L-Val-D-Hmb-N-methyl-L-Val-D-Hmb-)
  • ENNIATIN B
  • Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
  • 917-13-5
  • C33H57N3O9
  • Antibiotic
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