ACIFRAN

72420-38-3

CAS-Nr.: 72420-38-3

Englisch Name:: ACIFRAN

Synonyma:: ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid

CBNumber:: CB2121167

Summenformel:: C12H10O4

Molgewicht:: 218.21

MOL-Datei:: 72420-38-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 36

ACIFRAN Eigenschaften

Schmelzpunkt:: 176°

Siedepunkt:: 378.4±42.0 °C(Predicted)

Dichte: 1.343±0.06 g/cm3(Predicted)

storage temp.: Store at +4°C

Löslichkeit: Soluble in DMSO > 10 mM

Aggregatzustand: Powder

pka: 2.25±0.40(Predicted)

Sicherheit

Toxizität	LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)

ACIFRAN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Antihyperlipopro-teinemic.

Trademarks

Reductol (Wyeth-Ayerst).

Biologische Aktivität

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

ACIFRAN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2H-Pyran-2,3,5(4H,6H)-trione, 6-methyl-6-phenyl-

Downstream Produkte

ACIFRAN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 36)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2981	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Changzhou Chenhong Biotechnology Co., Ltd.	0519-85788828 13775037613	sales@chemrenpharm.com	China	3538	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1249	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

72420-38-3()Verwandte Suche:

2,3-Dihydro-5-methylfuran 2,3-Dihydrofuran 2,5-Dimethylfuran-3(2H)-on

ay25712
ACIFRAN
4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID
(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
Acifranum
4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci
5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid
2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-
72420-38-3
Miscellaneous Compounds